Oxidative Stress and Neurodegenerative Disorders Mamdouh Sample preparation

Sample preparation

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Oxidative Stress and Neurodegenerative Disorders Mamdouh Sample preparationOxidative stress is the result of an imbalance in pro oxidant antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to